Bone mass, density and geometry in phenylketonuria, reviewing the evidence | Evidence Summary
Description
The objective of this summary is to assess the available evidence relating to PKU and bone investigating the hypothesis that GMP-based protein substitutes are beneficial for bone health.
The aims of this review are to examine:
- How bone mass and density are defined and measured
- The current evidence
- Factors affecting bone in PKU including dietary management
- The effect of protein substitutes, including GMP